Research Scientist, Life Sciences (Chemistry)

Overview

Research Scientist (Life Sciences: Chemistry) to build end-to-end medicinal chemistry experiments that test AI-generated hypotheses and small-molecule designs.

What you'll do

• Design multi-step synthetic routes for small molecules and oversee execution end to end.
• Optimize reactions, purification strategy, and interpret characterization data (NMR, LC-MS, HPLC).
• Coordinate synthesis and biological evaluation with external CROs and academic partners.
• Evaluate AI-designed molecules and AI-proposed synthetic routes via experimental readouts and feedback to research teams.
• Apply medicinal chemistry principles (SAR analysis and physicochemical property optimization) for compound prioritization.
• Ensure data quality and documentation, including procedures, spectra, and failure modes.
• Communicate findings to chemistry, AI research, and life sciences audiences.

What you'll need

• PhD in chemistry.
• Demonstrated medicinal chemistry experience with SAR-driven design and optimization of small molecules.
• Recent, sustained hands-on synthetic work.
• Ability to navigate ambiguity and define problems in a rapidly evolving research environment.
• Ability to work independently while collaborating effectively across cross-functional teams.
• Strong written and verbal communication skills.

Details

• Fully on-site in the San Francisco Bay Area.