Purification Field Application Specialist

Overview

Field Applications Scientist providing technical support, training and scientific advisory for downstream protein purification and chromatography solutions, working with sales and customers across South Asia.

What you'll do

• Act as the regional subject-matter expert for downstream protein purification and chromatography applications.
• Provide hands-on technical support to strategic biopharmaceutical customers during evaluation, development and implementation of purification solutions.
• Design and support resin screening, process-development and optimization studies using POROS and CaptureSelect technologies.
• Support purification of monoclonal antibodies, recombinant proteins, bispecific antibodies, vaccines and other emerging biological modalities.
• Troubleshoot customer purification challenges involving yield, purity, aggregate removal, host-cell protein clearance, DNA removal, process robustness and productivity.
• Provide guidance on chromatography process parameters including residence time, loading, dynamic binding capacity, buffer conditions, elution, regeneration and CIP.
• Support column packing, qualification, scale-up and transfer of processes from development to pilot and manufacturing scale.
• Support integration of chromatography with filtration, TFF/UFDF and other downstream unit operations where appropriate.
• Develop scientific relationships with process-development scientists, downstream-processing leaders, manufacturing teams and technical decision-makers at key accounts.
• Translate customer process challenges into technically differentiated Thermo Fisher solutions and drive projects from initial technical discussion through product design-in.
• Provide sustained technical support for strategic programs through clinical development and commercial manufacturing.
• Serve as an escalation point for complex purification application issues within South Asia.
• Partner with sales, account management and business-development teams on pre-sales and post-sales activities.
• Build and manage a technical design-in pipeline for purification products across strategic accounts.
• Identify new opportunities for POROS, CaptureSelect and related purification technologies within existing and emerging customer processes.
• Support technical positioning and differentiation against competitive chromatography technologies.
• Track technical evaluations, customer milestones, design-ins and conversion opportunities.
• Champion new product introductions and emerging purification technologies across South Asia.
• Conduct seminars, workshops, webinars and customer training programs on chromatography and downstream processing.
• Represent Thermo Fisher Scientific at scientific conferences, industry meetings and technical forums.
• Utilize Thermo Fisher's Bioprocess Design Center capabilities to enable customer process-development, demonstration and training activities.
• Provide purification application leadership across South Asia and coordinate with APAC and global subject-matter experts.
• Mentor and technically support commercial and application colleagues on downstream-processing technologies.
• Lead technically complex, multi-site customer projects requiring coordination across commercial, product and application functions.

What you'll need

• Master's degree or Ph.D. in Biochemistry, Biotechnology, Bioengineering, Chemical Engineering, Biology, Chemistry or a related discipline.
• 7+ years of relevant experience in biopharmaceutical downstream process development, applications, manufacturing or technical support.
• Demonstrated hands-on experience developing purification processes for biologics.
• Strong practical understanding of protein chemistry and bioprocessing.
• Strong practical understanding of affinity chromatography, Protein A chromatography, ion-exchange chromatography (AEX and CEX), hydrophobic interaction chromatography, mixed-mode chromatography and size-exclusion chromatography.
• Strong practical understanding of chromatography resin screening and selection, dynamic binding capacity and breakthrough studies, column packing and qualification, process scale-up, resin cleaning and CIP strategies, buffer preparation and process optimization, and high-throughput purification-development approaches.
• Experience with chromatography systems and process-development platforms is expected.

Nice to have

• Advanced scientific or engineering training in downstream bioprocessing.
• Prior customer-facing or field-application experience.
• Experience working with biopharmaceutical process-development or manufacturing organizations.
• Experience supporting projects from laboratory development through scale-up or manufacturing.
• Knowledge of protein analytical techniques such as HPLC, SEC, electrophoresis/CGE, ELISA and related analytical tools.

Details

• Location: Bangalore, India.
• Standard work schedule Monday to Friday.
• Frequent travel to customer sites (50-70%) across India and South Asia.
• Some degree of PPE required (safety glasses, gowning, gloves, lab coat, ear plugs etc.) and exposure to various outside weather conditions.