Principal Scientist

Overview

Principal Scientist to help implement the strategic scientific plan for translational medicine research, primarily in immuno-oncology and autoimmune/inflammatory areas, leading flow cytometry and cell-based assay development and training junior scientists.

What you'll do

• Provide mentoring, coaching and team leadership to Flow Laboratory team members, hold one-on-one engagement meetings with direct reports, set goals, conduct performance reviews and set priorities for lab work.
• Motivate team, share knowledge on FACS, participate in recruitment process and revenue forecasting.
• Design and implement cell-based assays to meet client requirements, including complex flow immunophenotyping assays and primary cell based assays.
• Write and implement standard operating procedures (SOPs) to perform assays to meet client requirements and the level of regulatory compliance needed.
• Utilize current SOPs to perform cell assays such as flow immunophenotyping, ELISpot, and other custom cell based assays.
• Generate technical reports and other communications required to present data to clients.
• Write posters and papers for submission to conference organizers and peer reviewed journals.
• Write reviews and white papers.
• On occasion, review and edit client proposals, contracts and proposals as appropriate.
• Train scientific staff in the review and presentation of data, including client reports, posters and papers for peer reviewed journals.
• Train technical staff how to perform laboratory procedures, and devise and perform validation schema to ensure staff are superbly trained and competent.
• Maintain and support safe lab practices and environment.
• Track and trend laboratory efficiency and quality.
• Perform duties with high degree of independence, quality, and efficiency.
• Act as internal expert on technical advances and industry trends, and advise management on matters of major importance, initiating or recommending appropriate courses of action and identifying matters requiring policy interpretation or revision.
• Promote the company to local, regional, national, and international constituencies through networking, speaking engagements, activity in professional associations and publications.

What you'll need

• Ph.D. in life sciences or relevant field (Immunology or Cellular Biology preferred).
• At least 8 years of full-time post-doctoral laboratory experience.
• Strong bench scientist skills around cell-based assays.
• Hands-on flow cytometry experience.
• Core competencies of standard biology laboratory experience, e.g. cell isolation and primary cell based assays.
• Experience with cell sorting, trouble-shooting and client relationships, alliance partnerships and timelines.
• Experience in validation/qualification of assays to CAP/CLIA/GLP or ISO guidelines.
• Strong organizational skills.
• Strong communication skills.
• Experienced technical report generation.
• Ability to see and differentiate between colors on the full color spectrum.
• Ability to lift and carry 1-15 lbs; ability to lift up to 50 lbs overhead with assistance; frequently required to sit, grasp, and use right/left finger dexterity; may be exposed to a cold freezer environment (-20ºC to -196ºC).
• Must be able to read, write, speak fluently and comprehend the English language.

Nice to have

• Experience with ELISpot and other cell based assays.
• 10-15+ years' experience as CORE lab member with leadership role as direct manager to flow cytometry team.
• Industrial experience and/or management of outside collaborations.
• Experience with viral infections; cell culture and cell line derivation; nucleic acid (RNA and DNA) extraction from primary human samples; nucleic acid characterization by spectrophotometer, Agilent, and fluorescence-based detection.

Details

• Location: Bangalore, Karnataka, India.
• Candidates must be legally authorized to work in the country of employment without employer sponsorship.