Scientist I, Protein Biology

Overview

Join the antibody development team as a Scientist I focused on antibody performance and specificity, using molecular, protein, biochemical and cell biology methods.

What you'll do

• Plan and execute experiments meticulously to meet program goals.
• Record results accurately and promptly in data sheets and laboratory notebooks.
• Mine literature regularly and keep up to date with developments in antibody development.
• Compile and present data in written and oral formats.
• Participate actively in team meetings.
• Maintain attention to detail and adhere to schedules.

What you'll need

• Master's with 0-4 years of confirmed experience, or a PhD in a life sciences field (submitted within the last one year), with a strong focus on protein biology, protein design, protein purification, antibody or protein conjugations, molecular biology, immunology, biotechnology or biochemistry.
• Strong theoretical and working knowledge of protein expression, protein purification and antibody purification.
• Experience working with different expression systems, inclusion bodies and re-folding.
• Hands-on experience performing protein purification using affinity, ion-exchange and size exclusion chromatography.
• Experience in automated purification method development on AKTA, NGC and liquid handler.
• Characterization of proteins using SDS-PAGE and SEC-HPLC, and validation in immunoassays such as ELISA, western blot and IF.
• Experience or familiarity with protein engineering, rational design of mutants, and molecular biology.
• Experience with structural biology and protein modeling and visualization tools such as Pymol, Schrodinger, Discovery Studio or other such programs.
• Project or work experience in support of relevant skills, such as publications, project reports or thesis work.
• Proficiency in MS Office applications such as Word, PowerPoint and Excel, with strong statistical knowledge and familiarity with statistical software such as Prism.
• Self-motivated and a self-starter who learns and applies new concepts for process or product improvements.
• Excellent oral and written communication skills to connect with peers and leadership.
• Excellent teammate with the ability to work with diverse colleagues.

Details

• Work schedule: Standard, Monday to Friday.
• Environment: Laboratory setting, office.