Scientist I, Protein Biology

Overview

Scientist I, Protein Biology on the Antibody Team, focused on the engineering and development of antibodies with a deep emphasis on reagent quality and specificity.

What you'll do

• Design and execute immunoassays to support antibody development and validation programs.
• Plan and execute experiments meticulously to meet program goals.
• Record results in a timely manner into data sheets and laboratory notebooks.
• Maintain attention to detail and adhere to schedules.
• Communicate results clearly in team meetings, written reports, and data presentations.
• Regularly review literature and keep up to date with developments in antibody development.
• Troubleshoot technical challenges and propose practical solutions to keep projects moving.

What you'll need

• Degree in a relevant life sciences discipline (protein biology, molecular biology, biochemistry, immunology, biotechnology, or a related field) at one of the following levels: PhD (graduated within the last year), or Master's degree with a minimum of 3 years of relevant research experience.
• Demonstrated experience in immunoassay development and application testing, especially Immunocytochemistry (ICC) and Immunohistochemistry (IHC).
• Proficiency in Python, R, bioinformatics/computational biology and statistical tools such as Pymol, Chimera, BLAST, Alphafold, ggplot.
• Solid foundation in molecular biology techniques including nucleic acid extraction, PCR, cloning, sequence analysis, and vector design.
• Practical experience in standard mammalian or other specialized cell culture techniques supporting protein expression, antibody production, or related workflows.
• Proficiency in MS Office (Word, PowerPoint, Excel) and statistical software such as GraphPad Prism, ggplot.
• Track record of scientific output through peer-reviewed publications, project reports, or thesis work.
• Self-motivated and proactive self-starter with a strong drive for continuous learning and process/product improvement.
• Excellent written and oral communicator, capable of clearly conveying findings to peers, collaborators, and leadership.
• Collaborative team player who works effectively with diverse colleagues across functional and organizational boundaries.
• Adaptable and flexible in navigating a fast-paced, evolving research environment with shifting priorities.
• Detail-oriented with a commitment to scientific rigor, schedule adherence, and data integrity.

Nice to have

• Advanced expertise in microscopy, spatial biology platforms, and multiplexed IHC/IF/ISH, with experience developing and analyzing high-content tissue imaging assays for protein expression and cellular phenotyping.
• Proficiency in deep learning models and/or knowledge of large language models (LLMs), prompt engineering, and experience implementing these tools to biological questions.
• Theoretical or practical exposure to antibody development platforms such as hybridoma, single B-cell, display technologies, or other recombinant approaches.
• Experience with automated liquid-handling platforms, high-content imaging or other high-throughput methodologies.
• A strong, independent understanding of standard and emerging trends in the field.
• Experience with website and/or database design using platforms such as HTML, JavaScript, ShinyR, PowerApps.

Details

• Standard work schedule, Monday to Friday.
• Laboratory setting and office; work involves cold room/freezers at -22°F/-6°C.
• Adherence to Good Manufacturing Practices (GMP) and safety standards; some degree of PPE required (safety glasses, gowning, gloves, lab coat, ear plugs, etc.).